Tuomas Mirtti Selected Research

STAT5 Transcription Factor

10/2019	Positive STAT5 Protein and Locus Amplification Status Predicts Recurrence after Radical Prostatectomy to Assist Clinical Precision Management of Prostate Cancer.
6/2013	STAT5A/B gene locus undergoes amplification during human prostate cancer progression.
12/2010	N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.
1/2010	Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer.

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Tuomas Mirtti Research Topics

Disease

47	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 02/2006
25	Neoplasms (Cancer) 01/2022 - 02/2006
9	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 01/2009
5	Disease Progression 01/2022 - 01/2010
5	Neoplasm Metastasis (Metastasis) 01/2021 - 07/2007
4	Carcinoma (Carcinomatosis) 02/2013 - 03/2003
2	Lymphatic Metastasis 01/2022 - 01/2015
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2021 - 06/2015
2	Hyperaldosteronism (Conn Syndrome) 01/2021 - 12/2020
2	Kidney Neoplasms (Kidney Cancer) 01/2019 - 01/2016
2	Carcinogenesis 07/2018 - 02/2011
2	Renal Cell Carcinoma (Grawitz Tumor) 10/2016 - 01/2016
2	Prostatic Intraepithelial Neoplasia 07/2016 - 03/2003
1	Multiple Endocrine Neoplasia Type 2b (MEN 3) 01/2022
1	Inflammation (Inflammations) 01/2021
1	Hypertrophy 01/2021
1	Obesity 01/2021
1	Adenoma (Adenomas) 12/2020
1	Necrosis 01/2020
1	Insulin Resistance 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Thrombosis (Thrombus) 10/2016

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2011
10	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2006
9	Messenger RNA (mRNA)IBA 01/2021 - 02/2006
6	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 02/2011
5	AndrogensIBA 07/2022 - 07/2007
5	Pharmaceutical PreparationsIBA 01/2019 - 12/2011
4	STAT5 Transcription FactorIBA 10/2019 - 01/2010
3	Kallikreins (Kallikrein)IBA 01/2022 - 01/2017
3	CytokinesIBA 01/2021 - 05/2014
3	Androgen Antagonists (Antiandrogens)IBA 01/2020 - 02/2011
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2016 - 06/2008
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 05/2014
2	metomidateIBA 01/2021 - 12/2020
2	enzalutamideIBA 01/2020 - 03/2015
2	LipidsIBA 01/2019 - 12/2011
2	LigandsIBA 01/2016 - 01/2010
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 07/2007
2	DNA (Deoxyribonucleic Acid)IBA 03/2015 - 12/2010
2	Prostate-Specific Antigen (Semenogelase)IBA 03/2015 - 01/2015
2	Flutamide (Eulexin)FDA LinkGeneric 03/2015 - 02/2011
2	Phospholipases (Phospholipase)IBA 12/2011 - 03/2009
2	Arachidonic Acid (Vitamin F)IBA 02/2011 - 03/2009
2	Cadherins (E-Cadherin)IBA 09/2010 - 06/2010
1	MicroRNAs (MicroRNA)IBA 01/2022
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2022
1	HLA-DR Antigens (HLA-DR)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Eosine Yellowish-(YS) (Eosin)IBA 09/2021
1	Hematoxylin (Haematoxylon)IBA 09/2021
1	stage-specific embryonic antigen-4IBA 01/2021
1	AdipoRonIBA 01/2021
1	EpitopesIBA 01/2021
1	EndotoxinsIBA 01/2021
1	Fibronectins (Fibronectin)IBA 01/2021
1	LipopolysaccharidesIBA 01/2021
1	VaccinesIBA 01/2021
1	Interleukin-4 (Interleukin 4)IBA 01/2021
1	CD40 Ligand (CD40L)IBA 01/2021
1	AdiponectinIBA 01/2021
1	Adiponectin ReceptorsIBA 01/2021
1	Granzymes (Granzyme)IBA 01/2020
1	Interferon-gamma (Interferon, gamma)IBA 01/2020
1	Interleukin-2 (IL2)IBA 01/2020
1	Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric 10/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	Insulin (Novolin)FDA Link 01/2019
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019
1	Glycerolphosphate Dehydrogenase (Glycerol 3 Phosphate Dehydrogenase)IBA 01/2019
1	Heat Shock Transcription FactorsIBA 07/2018
1	Caveolin 1IBA 01/2018
1	PlasticsIBA 10/2017
1	Prednisone (Sone)FDA LinkGeneric 01/2017
1	Prednisolone (Predate)FDA LinkGeneric 01/2017
1	Dihydrotachysterol (AT 10)IBA 01/2017
1	navitoclaxIBA 01/2017
1	Calcibiotic Root Canal SealerIBA 01/2017
1	Docetaxel (Taxotere)FDA Link 01/2017
1	fibroblast growth factor 13IBA 07/2016
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 07/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016
1	Sunitinib (Sutent)FDA Link 01/2016
1	Angiopoietin-2IBA 01/2016
1	AngiopoietinsIBA 01/2016

Therapy/Procedure

19	Therapeutics 07/2022 - 06/2008
19	Prostatectomy (Retropubic Prostatectomy) 07/2022 - 02/2006
9	Cystectomy 01/2021 - 01/2009
8	Castration 01/2022 - 01/2010
2	Immunotherapy 01/2022 - 01/2020
2	Nephrectomy 01/2022 - 01/2016
2	Neoadjuvant Therapy 10/2017 - 04/2016
1	Radiotherapy 07/2022
1	Transurethral Resection of Bladder 01/2021
1	Drug Therapy (Chemotherapy) 01/2021
1	Adrenalectomy 12/2020
1	Precision Medicine 10/2019
1	Adjuvant Chemotherapy 04/2016
1	Lymph Node Excision (Lymph Node Dissection) 04/2016